when you get to where you fight the three vampires, you have to keep your distance from them so theyre attacks wont hurt you and rapidly shoot your pistols at them. after the two vampires on the sides are defeated, the middle one will transform. keep shooting your pistols at her, and when she swoops down to attack you, jump over her or roll away to dodge her, and keep shooting again. when she does her lightning attack, jump over it and then keep shooting again at her. if you dodge her moves correctly, you should successfully defeat her.
it would also be very useful if you purchase two life replenishers in the artilery area, so that if your life does go down low, you can use them and get full life back.
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